On materialism, nothing of ultimate significance takes place. Because of that atheism itself, and those adherents of atheism who strive to invent meaning and purpose, live within a belief system that is absurd, illogical and incoherent.
This need not be the case, for the answer is as close as their next heart-beat.
"Living the awareness of the risen Jesus is not a trivial pursuit for the bored and lonely or a defence mechanism enabling us to cope with the stress and sorrow of life. It is the key that unlocks the door to grasping the meaning of existence. All day and every day we believers are being reshaped into the image of Christ. Everything that happens to us is designed to this end. Nothing that exists can exist beyond the pale of His presence (“All things were created through Him and for Him” - Colossians 1:16), nothing is irrelevant to it, nothing is without significance in it.
Everything that is comes alive in the risen Christ. Everything - great, small, important, unimportant, distant, and near - has its place, its meaning and its value. Through union with Him, nothing is wasted, nothing is missing. There is never a moment that does not carry eternal significance - no action that is sterile, no love that lacks fruition, and no prayer that is unheard. “We know that by turning everything to their good, God cooperates with all those who love Him.” (Romans 8:28)."